Randomization in Clinical Trials: Theory and Practice by William F. Rosenberger, John M. Lachin
English | PDF | 2002 | 278 Pages | ISBN : 0471236268 | 11.4 MB
A unique overview that melds the concepts of conditional probability and stochastic processes into real-life applications
The role of randomization techniques in clinical trials has become increasingly important. This comprehensive guide combines both the applied aspects of randomization in clinical trials with a probabilistic treatment of properties of randomization. Taking an unabashedly non-Bayesian and nonparametric approach to inference, the book focuses on the linear rank test under a randomization model, with added discussion on likelihood-based inference as it relates to sufficiency and ancillarity. Developments in stochastic processes and applied probability are also given where appropriate. Intuition is stressed over mathematics, but not without a clear development of the latter in the context of the former.
