This fourth volume in the series Advances in Vision Research describes importance advancements in basics to translational research, including new therapeutics for genetic eye diseases. Recent US FDA approval of the first gene therapy for an inherited retinal disease, due to a mutation in the RPE65 gene, has led to an upsurge in translational eye research. The coverage in this volume includes corneal diseases, myopia, cataract, glaucoma, inherited retinal diseases, inherited optic neuropathy, and other genetic eye diseases. New developments such as the application of artificial intelligence in translational eye research are also discussed. All chapters are written by leading researchers working on eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume IV will be a major resource for all researchers, clinicians, clinical researchers, andallied eye health professionals with an interest in eye diseases around the globe. The first two volumes in the series described the state of the art in genetic eye research in Asia and the Pacific while the third focused on progress in Europe and the United States.

This textbook sheds new light on pathology in and around the orbit, which is typically an area where many medical disciplines overlap. Each physician brings a specific expertise, but the goal should be that the end result of all this input is much more than the sum of the parts. Collaboration, insight and overall knowledge of all parties involved are essential to achieve an optimal patient outcome.

This book provides a comprehensive description of the pathology of the head and neck region, concentrating especially on those pathologic entities that are unique to or characteristic of the head and neck. The new edition retains the ten chapters of the first edition, all updated and improved, and additionally contains seven entirely new chapters and a more detailed subject index. The number of illustrations has been substantially increased, and various lesions absent in the original edition have been included. Throughout, attention is paid to correlation of pathology with epidemiology, clinical features, pathogenesis, and molecular genetics. Differential diagnosis is addressed, and information is also provided on staging, prognosis, and therapy. The authors include foremost experts in the field, some of whom are senior members of the Working Group on Head and Neck Pathology of the European Society of Pathology.