"Muscle Cell and Tissue: Novel Molecular Targets and Current Advances" ed. by Kunihiro Sakuma

This book details some approaches to the treatment of muscle wasting. It reviews novel applications against pulmonary arterial hypertension such as cell reprogramming and the use of anticancer drugs that induce programmed cell death. This book will be of interest to professionals in clinical practice, medical and health care students, and researchers working in muscle-related fields of science.

The loss of skeletal muscle mass and strength substantially impairs physical performance and quality of life. Vascular smooth muscle cells (VSMCs) are the most prevalent cell types in blood vessels and serve critical regulatory roles.
This publication also introduces mathematical models concerning the molecular mechanism and targets of cyclic guanosine 3′,5′-monophosphate (cGMP) in the contraction of VSMCs.

Contents
1. Exercise Therapy for Patients with Heart Failure: Focusing on the Pathophysiology of Skeletal Muscle
2. Evidence for the Role of Cell Reprogramming in Naturally Occurring Cardiac Repair
3. Interventional Strategies to Delay Aging-Related Dysfunctions of the Musculoskeletal System
4. Strategies to Treat Pulmonary Hypertension Using Programmed Cell Death-Inducing Anti-Cancer Drugs without Damaging the Heart
5. Hypothenar Muscles and Guyon’s Canal
6. Molecular Mechanisms and Targets of Cyclic Guanosine Monophosphate (cGMP) in Vascular Smooth Muscles


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